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PV-neutralizing activity in serum after oral administration of Sabin 1
| Mouse strain | Substance | Route of administration | Amt of immunizing virus (PFU/mouse) | Neutralizing activitya |
|---|---|---|---|---|
| PVRTg21/ IfnarKO | DMEM | Oral | 0 | 0/6 |
| Sabin 1 | Oral | 3 × 108 | 0/4 | |
| Sabin 1 | Intravenous | 1 × 105 | 8/8 | |
| PVRTg21 | Sabin 1 | Oral | 3 × 108 | 0/6 |
Expressed as the number of mice whose serum showed neutralizing activity (≥16)/number of mice examined.
