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. 2007 May 23;81(15):8112–8121. doi: 10.1128/JVI.00006-07

FIG. 6.

FIG. 6.

The HK97 NS gene also attenuates virus replication in the context of the other internal HK97 genes due to the identity of the amino acids at 103 and 106 in the NS1A protein. (A) Growth curves of recombinant viruses containing either the wt or G2 (+) mutant HK97 NS gene and all HK97 genes except those encoding HA and NA. (B) The amount of IFN-β mRNA produced during single-cycle growth of the recombinant containing the wt HK97 NS gene relative to that produced by the recombinant containing the G2 (+) mutant HK97 NS gene.