TABLE 1.

Representative genes regulated by MVA or NYVAC in infected MDDC according to predicted biological function

Description	GenBank accession no.	Gene	Fold change in transcription
			MVA	NYVAC
IFN and IFN-induced genes
IFN-induced protein with tetratricopeptide repeats 4	NM_001549	IFIT4	52.45	3.37
IFN-induced protein with tetratricopeptide repeats 1	NM_001548	IFIT1	47.8	4.65
IFN-induced, hepatitis C virus-associated microtubular aggregate protein (44 kDa)	NM_006417	MTAP44	20.95	2.63
IRF-2	NM_002199	IRF2	6.54	3.48
IRF-7	NM_004031	IRF7	2.52	1.3
IFN-α1	NM_024013	IFNA1	2.51	1.92
Myxovirus (influenza virus) resistance 1, IFN-inducible protein p78 (mouse)	NM_002462	MX1	2.26	1.44
IRF-5	NM_002200	IRF5	−2.31	1.06
IFN-α-inducible protein 27	NM_005532	IFI27	−2.46	−1.62
IFN-γ-inducible protein 30	NM_006332	IFI30	−2.79	−2.79
Interleukins
IL-6 (IFN, beta 2)	NM_000600	IL6	4.05	1
IL-1α	NM_000575	IL1A	−1.43	2.01
IL-8	NM_000584	IL8	−2.9	−1.39
IL-1β	NM_000576	IL1B	−2.25	1.39
TNF (TNF superfamily, member 2)	NM_000594	TNF	52.21	6.79
Other cytokines
GRO2 oncogene (SCYB2), CXCL2	NM_002089	GRO2	6.58	2.22
Small inducible cytokine A3	NM_002983	SCYA3	4.22	1.12
Small inducible cytokine A5 (RANTES)	NM_002985	SCYA5	4.17	−1.17
Small inducible cytokine A4	NM_002984	SCYA4	3.74	−1.14
Colony-stimulating factor 2 (granulocyte-macrophage)	NM_000758	CSF2	3.13	−1.08
Apoptosis
Nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor α	NM_020529	NFKBIA	9.59	6.02
MAIL, NFKBIZ	NM_031419	MAIL	12.99	4.91
BCL2-associated athanogene 3	NM_004281	BAG3	8.42	1.28
Calpain 1, (mu/I) large subunit	NM_005186	CAPN1	4.1	1.78
Antiviral immune response
Melanoma differentiation-associated protein 5	NM_022168	MDA5	7.77	1.67