FIG. 3.

PBMC IFN-γ ELISPOT responses in the vaccinated and control monkeys following viral challenge. Freshly isolated PBMCs were assessed for IFN-γ ELISPOT responses after in vitro exposure to peptide pools spanning the SIVmac251 Gag and HIV-1 89.6P Env proteins at weeks 2 (Wk 2 PC), 4 (Wk 4 PC), and 80 (Wk 80 PC) following intravenous SHIV-89.6P challenge. The bars represent the means ± standard errors of the means (error bars) of values of SFC responses to individual viral proteins for six monkeys in each group of experimentally vaccinated as well as control-vaccinated animals. PC, postchallenge.