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MAb binding epitopes shown on the three-dimensional model of Modis et al. (37). Two adjacent L1 pentamers are shown in gray and yellow. The carboxyl-terminal arm, originating from the yellow pentamer and extending toward the gray pentamer, is indicated in orange and red. MAb binding epitopes are indicated, in addition to our proposed ECM- and HSPG-binding regions. (Reprinted from the EMBO Journal [37] with permission from the publisher.)
