Virologic and immunologic measurements in R5 SHIVSF162P3N-infected RM CD80, T799, and BR24. (A) Viral load and absolute CD4+ T-cell counts. (B) Percentages of CD4+ T cells in the inguinal (Ing), iliac (Ili), mesenteric (Mes), and colonic (Col) lymph nodes and LPLs from the jejunum during peak (week 2) and chronic (week 20) stages of infection and at time of necropsy. Baseline values generated from three uninfected macaques are shown for reference. +, death due to euthanasia. Surgery was not performed on BR24 at week 20 due to the development of clinical signs consistent with SAIDS.