TABLE 2.

Hydrogen bonding distances between protease and inhibitor atoms in the crystal structure of the lysine sulfonamide (compound 8)

Protease atom	Inhibitor atom	Distance (Å)
Asp30′ OD2	N45	2.8
Water 40	N45	2.9
Water 69	N45	3.1
Ile50 N	O8	3.1
Ile50′ N	O9	2.9
Asp25 OD1	O23	3.1
Asp25 OD2	O23	2.7
Asp25′ OD1	O23	2.9
Asp25′ OD2	O23	2.6
Gly48 O	N21	2.8
Asp29 OD2	N38	2.9
Asp29 N	O40	2.9
Asp29 OD2	O42	3.3
Water 37	O42	2.8
Gly48 N	O43	3.1