TABLE 1.

Demographic, clinical, and virological profiles of participants at enrollment

Parameter	Value (% or range)
	HIV-1/2	HIV-1a,b	HIV-2a
No. of subjects	19	112	78
No. female	18 (95)	93 (85)	62 (79)
Mean age in yr	41 (26-57)	34 (16-55)	41 (26-68)
Mean CD4+ T-cell count (IQR cells/μl)	329 (133-461)	461 (332-538)	543 (240-827)
Mean CD8+ T-cell count (IQR cells/μl)	1,088 (649-1532)	965 (601-1235)	717 (450-840)
HIV-1 plasma RNA (log10 copies/ml)
Mean RNA	4.29	3.84	NAc
<1,000	5 (26)	21 (19)	NA
1000-10,000	2 (11)	33 (29)	NA
10,000-100,000	2 (11)	37 (33)	NA
>100,000	10 (53)	21 (19)	NA
HIV-2 plasma RNA (log10 copies/ml)
Mean RNA	2.23	NA	2.35
<100	10/14 (71)	NA	34/56 (61)
100-1,000	1/14 (7)	NA	9/56 (16)
>1,000	3/14 (21)	NA	13/56 (23)
WHO clinical stage (no. at stage/total no.)
1	6/19 (32)	60/109 (55)	41/77 (53)
2	3/19 (16)	22/109 (20)	12/77 (16)
3	9/19 (47)	25/109 (23)	21/77 (27)
4	1/19 (5)	2/109 (2)	3/77 (4)
Study populations
Commercial sex worker STD clinic
No. of subjects	12	33	26
Mean CD4+ T-cell count (cells/μl)	453	453	813
Mean HIV-1 plasma RNA (log10 copies/ml)	3.35	3.56	NA
Mean HIV-2 plasma RNA (log10 copies/ml)	2.52	NA	2.11
WHO clinical stage (no. at stage/total no.)
1	6/12 (50)	25/32 (78)	20/26 (77)
2	2/12 (11)	5/32 (16)	2/26 (8)
3	4/12 (33)	2/32 (6)	4/26 (15)
4	0/12 (0)	0/32 (0)	0/26 (0)
Infectious disease clinic patients
No. of subjects	7	79	52
Mean CD4+ T-cell count (cells/μl)	116	465	408
Mean HIV-1 plasma RNA (log10 copies/ml)	5.57	3.96	NA
Mean HIV-2 plasma RNA (log10 copies/ml)	1.70	NA	2.49
WHO clinical stage (no. at stage/total no.)
1	0/7 (0)	35/77 (45)	21/51 (41)
2	1/7 (14)	17/77 (22)	10/51 (20)
3	5/7 (71)	23/77 (30)	17/51 (33)
4	1/7 (14)	2/77 (3)	3/51 (6)

^aIn a subset of 68 HIV-1 and 55 HIV-2 singly infected patients that were described previously (33).

^bWe only enrolled HIV-1-infected patients with CD4⁺ T-cell counts of more than 350 cells/μl.

^cNA, not applicable.