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Human Ig germ line genes most closely related to chimpanzee heavy and light chains of anti-A33 MAbs
| MAb | Germ line gene in:a
|
||||||
|---|---|---|---|---|---|---|---|
| VH family | Segment
|
Vλ family | Segment
|
||||
| VH | D | JH | Vλ | Jλ | |||
| 6C | VH7 | VI-4.1B | D3-10 | J5b | VλI | 1b.366F5 | Jλ 3b |
| 12C | VH1 | DP-25 | D3-10 | J4b | VλIII | 3r.9C5 | Jλ 2/3a |
| 12F | VH5 | DP-73 | D3-3 | J5b | VλII | 2a2.272A12 | Jλ 2/3a |
The closest human VH and Vλ germ lines were identified by the V-Base database.
