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Comparison of levels of IFN produced by BL6 and IRF3−/− mice following inoculation with WNV VLPs by different routes. Pairs of mice were injected by the i.p. or f.p. route with the indicated doses of WNV VLPs. After 24 h, sera were collected and IFN levels were determined by bioassay (filled and open bars represent the values obtained for the two mice in each group).
