FIG. 3.
Glucose tolerance and insulin sensitivity of SSAT and Wt mice. An intraperitoneal (ip) glucose tolerance test with 2 mg/mg glucose was performed on fasted, nonanesthetized, 3- to 4-month-old female SSAT and Wt mice. (A) Glucose and (B) insulin concentrations during the intraperitoneal glucose tolerance test. Intraperitoneal insulin tolerance tests with (C) 0.25 mU/g insulin and (D) 0.15 mU/g insulin and 0.4 mg/g glucose were performed on fasted, nonanesthetized, 3- to 4-month-old female SSAT and Wt mice. Results are presented as means ± SEM from five to six mice per group. *, P < 0.05; **, P < 0.01; ***, P < 0.001.