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Structure of the human retrotransposon L1. (A) Schematic representation of the human L1 dicistronic mRNA. (B) Computer-predicted secondary structure of the L1 5′UTR. The overall structure was evaluated using MFold software (64). The potential pseudoknot at the 5′-proximal part was suggested by pknotsRG (41). The last ∼100 nt of the 5′UTR, predicted to form no significant secondary structure, are shown by a dotted line.
