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Lack of UBPy causes progressive liver injury. (A) Morphological analysis of liver sections. Paraffin sections were stained with hematoxylin and eosin. Abbreviations are as follows: CV, central vene; CB, Councilman bodies; S, liver sinosoid. (B) Enhanced apoptosis in hepatocytes lacking UBPy. TUNEL staining was performed 4 days after poly(I·C) induced UBPy deletion.
