FIG. 5.
EAP1 expression affects biofilm formation in a rat central venous catheter model. Scanning electron microscopy images of C. albicans strain YJB6284 (EAP1/EAP1), SPY313 (eap1Δ/EAP1), SPY314 (eap1Δ/eap1Δ), and SPY315 (eap1Δ/eap1Δ/EAP1) biofilm cross sections formed in a rat central venous catheter model. Catheters were conditioned for 24 h, 5 × 105 CFU were instilled into the catheters, and biofilms were allowed to develop for 24 h. Catheter segments were fixed overnight and dehydrated by a series of ethanol washes. Samples were observed in the high-vacuum mode at 10 kV. Bar = 30 μm.