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. Author manuscript; available in PMC: 2007 Aug 24.
Published in final edited form as: Neuroscience. 2007 Mar 23;146(2):697–712. doi: 10.1016/j.neuroscience.2007.02.025

Fig. 3.

Fig. 3

The action of PACAP38 on granule cell migration in the ML of P10 mouse cerebella depends on the activity of the cAMP- and Ca2+- signaling pathways. (A) Histograms showing the alterations of the effects of 1μM PACAP38 on the rate of granule cell migration in the ML by application of 100 μM Rp-cAMPS, 5 μM PKI, 1 μM U73122, and 1 μM somatostatin 14 (SST-14). Each column represents the average values obtained from at least 30 migrating cells. Bar: S.D. (B) Changes in intracellular Ca2+ transients of the somata of migrating granule cells in the ML of the P10 mouse cerebella by application of 1 μM PACAP38. (C1 and C2) Histograms showing the changes in the frequencies (C1) and amplitudes (C2) of Ca2+ transients in the granule cell somata in the ML of the P10 mouse cerebella by application of 1 μM PACAP38. Each column represents the average values obtained from at least 30 migrating cells. Bar: S.D.