Table 1.
Predicted results of overexpression suppression analysis of Lte1 regulators in the checkpoint pathway
| Deletion | Overexpression |
|||||
|---|---|---|---|---|---|---|
| KIP2 | BUD6 | ATC1 | MSL1 | LTE1 | Control | |
| kip2Δ | NA | + | + | + | − | − |
| bud6Δ | − | NA | + | + | − | − |
| atc1Δ | − | − | NA | + | − | − |
| msl1Δ | − | − | − | NA | − | − |
| lte1Δ | + | + | + | + | NA | + |
Results shown are for checkpoint integrity, based on a linear pathway. In an arp1Δ GFP-TUB1 background, the indicated genes in the first row were overexpressed by integrating the GAL1 promoter at the endogenous locus and adding galactose to the medium. Control is a strain without an integrated GAL1 promoter. The first column lists the null mutant haploid strains tested. +, suppression of the loss-of-checkpoint phenotype; −, no suppression.