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Modular structures of E. coli and P. aeruginosa PBP 2 constructs. Each is composed of an N-terminal transmembrane anchor (TM), followed by an n-PB module and then a C-terminal PB module. The position of the consensus SxxK sequence, corresponding to the catalytic Ser of the PB module, is identified. The names of plasmids encoding the wild-type and mutant derivatives of the PBPs are listed at left.
