FIG. 4.
Comparison of interfaces in RIEF fold proteins. The β-sheets in the RIEF folds are shown in cyan and are depicted in the same orientation as the RimM.1-85 structure shown in Fig. 3C. The target nucleotides and proteins are partially displayed and are colored yellow and green, respectively. The characteristic structural elements in translation proteins are colored navy. (A) RimM.1-85. (B) Domain II of T. aquaticus EF-Tu with Phe-tRNAPhe (PDB identifier 1TTT) (31). (C) Domain II of archaeal aIF2γ with domain 3 of aIF2α (PDB identifier 2AHO) (37). (D) Topology diagrams of RimM.1-85 (left) and translation proteins (right). The six common strands are cyan, and the dissimilar secondary structures, namely helices and strands, are red and navy, respectively.