(A) Organ weights. The organs indicated were dissected from 23- to 41-week-old female mice, and the average weight and standard deviation were determined. Black, wild type, n = 5; light gray, p27D51/D51, n = 6; dark gray, p107−/−, n = 5; white, p107−/− p27D51/D51, n = 3. (B) Thymocytes from 8- to 10-week-old mice were collected, and the total cell number was determined. The mean number of thymocytes and the standard deviation are shown. Asterisks indicate those values significantly different (P < 0.01) from wild-type mice based on a two-tailed Student's t test.