TABLE 1.
Genotype of 644 embryos and 240 F2 mice from 114 Erfdl1/+ × Erfdl1/+ intercrosses of mixed C57BL/6 × 129/Sv or 129/Sv backgrounda
| Stageb | No. of litters | No. of embryos | No. (%) with genotype:
|
Comment | ||
|---|---|---|---|---|---|---|
| +/+ | dl1/+ | dl1/dl1 | ||||
| E8.5 | 10 | 79 | 20 (25) | 41 (52) | 18 (23) | |
| E9 | 4 | 30 | 7 (23) | 14 (47) | 9 (30) | |
| E9.5 | 42 | 376 | 82 (22) | 179 (48) | 116 (31) | |
| E10 | 5 | 42 | 8 (19) | 23 (55) | 11 (26) | |
| E10.5 | 10 | 89 | 19 (21) | 47 (53) | 23 (26) | 22 of the Erfdl1/dl1 embryos were dead |
| E11.5 | 3 | 28 | 8 | 17 | 3 | 5 Resorbtions |
| F2 | 40 | 240 | 88 (37) | 152 (63) | 0 | |
a
The viability status of the embryos was determined by their heartbeat at the moment of dissection.
b
E8.5, embryonic day 8.5.