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. 2007 May 7;27(14):5120–5127. doi: 10.1128/MCB.00215-07

FIG. 2.

FIG. 2.

Bsx-lacZ expression in the embryonic and postnatal brain. (A to C) Bsx-lacZ expression was detected as a blue spot in the temporal region of E13.5 mouse brains (black arrows). (D to G) Bsx-lacZ expression was detected in the pineal gland (black arrows) and the hypothalamus (ventral view) of P2 mouse brains. Ectopic Bsx-lacZ expression was detected in the ventral preoptic region of Bsx homozygous mutant mice (white arrow). (H to J) Bsx-lacZ expression was detected in the caudal region of the hypothalamus at P21. The expression around the third ventricle was extended caudally in homozygous mutants compared to heterozygous mutants (black arrowheads). The expression in the lateral region was reduced in homozygous mutants (white arrowheads). on, optic nerve; h, hypothalamus; p, pons; +/+, wild-type; z/+, BsxlacZ heterozygote; z/z, BsxlacZ homozygote; z/−, BsxlacZ/BsxΔHD.