Skip to main content
Applied and Environmental Microbiology logoLink to Applied and Environmental Microbiology
. 1992 Jan;58(1):233–236. doi: 10.1128/aem.58.1.233-236.1992

Fate of Fumonisin B1 in Naturally Contaminated Corn during Ethanol Fermentation

R J Bothast 1,*, G A Bennett 1, J E Vancauwenberge 1, J L Richard 1
PMCID: PMC195197  PMID: 16348623

Abstract

Two lots of corn naturally contaminated with fumonisin B1 (15 and 36 ppm) and a control lot (no fumonisin B1 detected) were used as substrates for ethanol production in replicate 8.5-liter yeast fermentations. Ethanol yields were 8.8% for both the control and low-fumonisin corn, while the high-fumonisin corn contained less starch and produced 7.2% ethanol. Little degradation of fumonisin occurred during fermentation, and most was recovered in the distillers' grains, thin stillage, and distillers' solubles fractions. No toxin was detected in the distilled alcohol or centrifuge solids. Ethanol fermentation of fumonisin-contaminated corn coupled with effective detoxification of distillers' grains and aqueous stillage is suggested as a practical process strategy for salvaging contaminated corn.

Full text

PDF
233

Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Bothast R. J., Nofsinger G. W., Lagoda A. A., Black L. T. Integrated process for ammonia inactivation of aflatoxin-contaminated corn and ethanol fermentation. Appl Environ Microbiol. 1982 Apr;43(4):961–963. doi: 10.1128/aem.43.4.961-963.1982. [DOI] [PMC free article] [PubMed] [Google Scholar]
  2. Chu F. S., Chang C. C., Ashoor S. H., Prentice N. Stability of aflatoxin B-1 and ochratoxin A in brewing. Appl Microbiol. 1975 Mar;29(3):313–316. doi: 10.1128/am.29.3.313-316.1975. [DOI] [PMC free article] [PubMed] [Google Scholar]
  3. Gelderblom W. C., Jaskiewicz K., Marasas W. F., Thiel P. G., Horak R. M., Vleggaar R., Kriek N. P. Fumonisins--novel mycotoxins with cancer-promoting activity produced by Fusarium moniliforme. Appl Environ Microbiol. 1988 Jul;54(7):1806–1811. doi: 10.1128/aem.54.7.1806-1811.1988. [DOI] [PMC free article] [PubMed] [Google Scholar]
  4. Harrison L. R., Colvin B. M., Greene J. T., Newman L. E., Cole J. R., Jr Pulmonary edema and hydrothorax in swine produced by fumonisin B1, a toxic metabolite of Fusarium moniliforme. J Vet Diagn Invest. 1990 Jul;2(3):217–221. doi: 10.1177/104063879000200312. [DOI] [PubMed] [Google Scholar]
  5. Jackson M. A., Bennett G. A. Production of fumonisin B1 by Fusarium moniliforme NRRL 13616 in submerged culture. Appl Environ Microbiol. 1990 Aug;56(8):2296–2298. doi: 10.1128/aem.56.8.2296-2298.1990. [DOI] [PMC free article] [PubMed] [Google Scholar]
  6. Krogh P., Hald B., Gjertsen P., Myken F. Fate of ochratoxin A and citrinin during malting and brewing experiments. Appl Microbiol. 1974 Jul;28(1):31–34. doi: 10.1128/am.28.1.31-34.1974. [DOI] [PMC free article] [PubMed] [Google Scholar]
  7. Lillehoj E. B., Lagoda A., Maisch W. F. The fate of aflatoxin in naturally contaminated corn during the ethanol fermentation. Can J Microbiol. 1979 Aug;25(8):911–914. doi: 10.1139/m79-135. [DOI] [PubMed] [Google Scholar]
  8. Marasas W. F., Kriek N. P., Fincham J. E., van Rensburg S. J. Primary liver cancer and oesophageal basal cell hyperplasia in rats caused by Fusarium moniliforme. Int J Cancer. 1984 Sep 15;34(3):383–387. doi: 10.1002/ijc.2910340315. [DOI] [PubMed] [Google Scholar]
  9. Nelson P. E., Plattner R. D., Shackelford D. D., Desjardins A. E. Production of fumonisins by Fusarium moniliforme strains from various substrates and geographic areas. Appl Environ Microbiol. 1991 Aug;57(8):2410–2412. doi: 10.1128/aem.57.8.2410-2412.1991. [DOI] [PMC free article] [PubMed] [Google Scholar]
  10. Nip W. K., Chang F. C., Chu F. S., Prentice N. Fate of ochratoxin A in brewing. Appl Microbiol. 1975 Dec;30(6):1048–1049. doi: 10.1128/am.30.6.1048-1049.1975. [DOI] [PMC free article] [PubMed] [Google Scholar]
  11. Nofsinger G. W., Bothast R. J. Ethanol production by Zymomonas mobilis and Saccharomyces uvarum on aflatoxin-contaminated and ammonia-detoxified corn. Can J Microbiol. 1981 Feb;27(2):162–167. doi: 10.1139/m81-026. [DOI] [PubMed] [Google Scholar]
  12. Ross P. F., Nelson P. E., Richard J. L., Osweiler G. D., Rice L. G., Plattner R. D., Wilson T. M. Production of fumonisins by Fusarium moniliforme and Fusarium proliferatum isolates associated with equine leukoencephalomalacia and a pulmonary edema syndrome in swine. Appl Environ Microbiol. 1990 Oct;56(10):3225–3226. doi: 10.1128/aem.56.10.3225-3226.1990. [DOI] [PMC free article] [PubMed] [Google Scholar]
  13. Ross P. F., Rice L. G., Plattner R. D., Osweiler G. D., Wilson T. M., Owens D. L., Nelson H. A., Richard J. L. Concentrations of fumonisin B1 in feeds associated with animal health problems. Mycopathologia. 1991 Jun;114(3):129–135. doi: 10.1007/BF00437200. [DOI] [PubMed] [Google Scholar]
  14. Thiel P. G., Marasas W. F., Sydenham E. W., Shephard G. S., Gelderblom W. C., Nieuwenhuis J. J. Survey of fumonisin production by Fusarium species. Appl Environ Microbiol. 1991 Apr;57(4):1089–1093. doi: 10.1128/aem.57.4.1089-1093.1991. [DOI] [PMC free article] [PubMed] [Google Scholar]
  15. Wilson T. M., Ross P. F., Rice L. G., Osweiler G. D., Nelson H. A., Owens D. L., Plattner R. D., Reggiardo C., Noon T. H., Pickrell J. W. Fumonisin B1 levels associated with an epizootic of equine leukoencephalomalacia. J Vet Diagn Invest. 1990 Jul;2(3):213–216. doi: 10.1177/104063879000200311. [DOI] [PubMed] [Google Scholar]

Articles from Applied and Environmental Microbiology are provided here courtesy of American Society for Microbiology (ASM)

RESOURCES