TABLE 6.
Categorization of H. pylori-gastric epithelium interactions in C57BL/6 mice infected for 6 monthsa
Strain | % Touching | % Near | % Distant | N |
---|---|---|---|---|
Wild-type SS1 | 87.6 | 9.0 | 3.4 | 276 |
SS1 cheW | 53.4 | 24.9 | 21.7 | 178 |
SS1 cheY | 70.6 | 17.9 | 11.4 | 243 |
SS1 tlpA | 74.2 | 14.6 | 11.2 | 474 |
SS1 tlpB | 63.0 | 22.2 | 14.8 | 1,005 |
The mouse samples were the same samples that were used for the experiments whose results are shown in Fig. 1 and Table 3. Categories are defined in the text. N is the number of bacteria examined; for each strain five or six mouse stomach sections (each from an individual mouse) were examined, and all visible helical bacteria were placed into one of the three categories. The data were analyzed using a chi-square test to compare the distribution between the three categories to a distribution that would occur randomly. The analysis indicated that the differences in frequency observed between groups have a very low probability of being generated by random chance (P < 0.00001) from a single theoretical frequency distribution.