FIG. 5.
Serovar Typhimurium (STm) 4/74 induces elevated levels of proinflammatory cytokine mRNAs compared to serovar Choleraesuis (SCS) early after oral inoculation of pigs. Data represent the mean 40-Ct values (a measurement of the abundance of cytokine mRNAs) for porcine TNF-α, IL-8, and IL-18 mRNAs in ileal mucosa 24, 48, and 72 h after oral inoculation of pigs with serovar Typhimurium 4/74 or serovar Choleraesuis A50 or mock infection relative to that for 28S rRNA. The mean was derived from independent determinations from at least three pigs at each time interval ± the standard error of the mean. *, P < 0.05 for elevated transcript levels induced by serovar Typhimurium 4/74 compared to those induced by serovar Choleraesuis A50 at 24 h postinfection. UI, uninfected.