TABLE 1.
Recognition of individual peptides by serum and intestinal antibodies from vaccinated baboonsa
| Antibody group | OD readingb for indicated LC3 peptide
|
|||
|---|---|---|---|---|
| 2 (aa 891-903) | 9 (aa 918-939) | 11 (aa 1114-1138) | 12 (aa 1128-1150) | |
| Fecal antipeptide IgA | 1.829 | 0.735 | 0.0 | 0.783 |
| Serum antipeptide IgA | 0.904 | 3.706 | 0.168 | 1.334 |
| Serum antipeptide IgG | 0.518 | 3.701 | 2.149 | 3.742 |
a
Serum and fecal samples from the six baboons immunized with the 1,600-μg dose of polylysine-linked synthetic peptides were pooled and studied in duplicate.
b
A positive result was defined as a reading ≥4-fold higher than the OD reading for control baboon sera. aa, amino acids.