TABLE 3.
Borrelia purine metabolism genes and ORF designations
| Gene product | Gene | ORF designation in:
|
||
|---|---|---|---|---|
| B. burgdorferi B31 | B. hermsii DAH | B. turicatae 91E135 | ||
| Hypoxanthine-guanine PRT | hpt | BH0421-A | BT0421-A | |
| Adenylosuccinate synthase | purA | BH0421-B | BT0421-B | |
| Adenylosuccinate lyase | purB | BH0421-C | BT0421-C | |
| Auxiliary (NrdI) protein | nrdI | BHP76-A | BTP76-A | |
| Ribonucleotide-diphosphate reductase alpha subunit | nrdE | BHP76-B | BTP76-B | |
| Ribonucleotide-diphosphate reductase beta subunit | nrdF | BHP76-C | BTP76-C | |
| Adenine PRT | apt | BB0777 | BH0777 | BT0777 |
| PRT | prt | BB0103 | BH0103 | BT0103 |
| GMP synthase | guaA | BBB18 | BHP-B18 | BTP-B18 |
| IMP dehydrogenase | guaB | BBB17 | BHP-B17 | BTP-B17 |
| Adenine deaminase | ade | BBK17 (BBH33) | Pseudogene | BTP-K17 |
| Guanine-hypoxanthine permease | pbuG | BBB22, BBB23 | BHP-B22 | BTP-B22 |
| Adenylate kinase | adk | BB0417 | BH0417 | BT0417 |
| Nucleoside-diphosphate kinase | ndk | BB0463 | BH0463 | BT0463 |