TABLE 2.

Comparison of structures of P. furiosus ACAPT with homologues

Source of enzyme	% Sequence identity	Sequence length (amino acids)	PDB IDa	PDB IDb	RMSD (Å)c
P. furiosus	100	271-271	1MJF_A	1MJF_B	0.35
C. elegans	39	276-276	1MJF	2B2C	1.53-1.57
T. maritima	35	264-271	1MJF	1INL	1.51-1.56
T. maritima	35	264-295	1MJF	1JQ3	1.49-1.55
T. thermophilus	33	263-313	1MJF	1UIR	1.64-1.72
H. sapiens	33	279-286	1MJF	1ZDZ	1.56-1.62
A. thaliana	32	263-290	1MJF	1XJ5	1.47-1.55
B. subtilis	30	259-274	1MJF	1IY9	1.42-1.56

^aPDB ID, Protein Data Bank identification.

^b1JQ3 is a complex between the enzyme and a substrate analogue.

^cRange based on superposition of equivalent Cα positions for all protein chains in the entry. RMSD, root mean square deviation.