TABLE 1.
C. elegans candidate antimicrobial genes characterized
| Gene name | Gene ID | Gene description | Expression pattern |
|---|---|---|---|
| lys-1 | Y22F5A.4 | Lysozyme | Intestine, head neurons including one in amphid, two phasmid neurons |
| lys-7 | C02A12.4 | Lysozyme | Intestine, rectal gland cells, head neurons |
| lys-8 | C17G10.5 | Lysozyme | Intestine, head and tail neurons |
| spp-1 | T07C4.4 | Saposin-like | Intestine |
| spp-7 | ZK616.9 | Saposin-like | Pharyngeal muscles (pm7), intestine (posterior > anterior), head neurons |
| abf-1 | C50F2.9 | Homolog of the antibacterial factor ASABF from Ascaris suum | Intestine, weak pharyngeal lumen, head neurons including one in amphid |
| abf-3 | F54B8.5 | Homolog of the antibacterial factor ASABF from Ascaris suum | Intestine, rectal gland cells |
| clec-85 | Y54G2A.6 | C-type lectin | Intestine |
| nlp-29 | B0213.4 | Originally classified as neuropeptide-like protein | Epidermal syncytia but not seam cells |
| F55G11.4 | F55G11.4 | Contains similarity to Pfam domain PF02408 (CUB-like domain) | |
| F08G5.6 | F08G5.6 | Contains similarity to Pfam domain PF02408 (CUB-like domain) | Intestine, head neurons |
| dod-22 | F55G11.5 | Contains similarity to Pfam domain PF02408 (CUB-like domain) | Intestine, rectal gland cells, head neurons |
| F10A3.4 | F10A3.4 | Contains similarity to Pfam domain PF02408 (CUB-like domain) | Intestine, tail neurons |
| F54B11.11 | F54B11.11 | Contains similarity to Pfam domain PF02408 (CUB-like domain) | |
| F55G11.7 | F55G11.7 | Contains similarity to Pfam domain PF02408 (CUB-like domain) | Intestine, rectal gland cells, head neurons including one in amphid, a phasmid neuron |
| K08D8.5 | K08D8.5 | Contains similarity to Pfam domain PF02408 (CUB-like domain) | Intestine, rectal gland cells, head neurons |