FIG. 4.

Changes in Bdf1 and Taf1 occupancy when Gcn5 is eliminated. ChIP-chip assays were performed with Bdf1-TAP and Taf1-TAP as described in the legend to Fig. 2A; the test and reference samples were derived from gcn5Δ and GCN5 strains, respectively. The average n-fold change in occupancy between the mutant and wild-type strains was determined for the set of genes in clusters 1 to 4 (Fig. 2A), log₂ transformed, and plotted. The data were centered such that there was, on average, no change in occupancy in nonpromoter intergenic regions. “All” denotes the value for all intergenic promoter regions for which there were valid data.