FIG. 3.
Food intake and serum glucose, insulin, and leptin levels in adult Grb10Δ2-4m/+ (m-het) and wild-type (wt) animals. (A) Food consumption (grams food per gram of body weight per day) of 6-month-old male and female mice. (B) Serum glucose, insulin, and leptin concentrations in free-fed 6-month-old males. (C) Serum leptin concentration normalized for WAT mass. (D) Correlation between serum leptin levels and total body weight for wild-type (wt; P = 0.0005) and Grb10Δ2-4m/+ (m-het; P = 0.1416 [nonsignificant]) assessed using a two-tailed Spearman's rank correlation test. All results are expressed as means ± SEM and were compared using ANOVA, except as stated for panel D (*, P < 0.05).