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Frequency of live progeny from Apaf-1 and Smac heterozygous intercrosses at E16.5
| Genotype | No. (%) of live embryos expected | No. (%) of live embryos observed |
|---|---|---|
| Controla | 168 (56.25) | 172 (57.72) |
| Apaf-1−/−b | 56 (18.75) | 49 (16.44) |
| Smac−/− | 56 (18.75) | 61 (20.47) |
| Apaf-1−/− Smac−/−c | 18 (6.25) | 16 (5.37) |
Includes Apaf-1+/± and/or Smac+/± genotypes.
Eight of 49 (16.32%) embryos had protruded brain morphology.
Three of 16 (18.75%) embryos had protruded brain morphology.
