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. 2007 Jun 11;27(16):5737–5745. doi: 10.1128/MCB.02265-06

FIG. 2.

FIG. 2.

Hypoxic increase in cytosolic ROS does not induce DNA double-stranded break response. (a) Relative intracellular H2O2 levels of PHLFs, as determined by Amplex Red in 21% O2, 3% O2, or 1.5% O2. *, P < 0.05 for 3% O2 or 1.5% O2 compared to 21% O2 (n = 3). (b) Phosphorylation status of H2AX in acid-extracted proteins from PHLF exposed to 21% O2, 3% O2, 1.5% O2, or staurosporine.