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. 2007 Sep 5;2(9):e850. doi: 10.1371/journal.pone.0000850

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This is an open-access article distributed under the terms of the Creative Commons Public Domain declaration which stipulates that, once placed in the public domain, this work may be freely reproduced, distributed, transmitted, modified, built upon, or otherwise used by anyone for any lawful purpose.

This is an open-access article distributed under the terms of the Creative Commons Public Domain declaration, which stipulates that, once placed in the public domain, this work may be freely reproduced, distributed, transmitted, modified, built upon, or otherwise used by anyone for any lawful purpose.

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Each point is the ratio of the estimated 97.5^th percentile antibody response to the 2.5^th percentile response (i.e. the 95% range) in the post vaccination sera. Most vaccine trials contained several immunogens. Eleven serospecificites are reported for pneumonococcal vaccines. The order from top to bottom is serotypes 1, 3, 4, 5, 6B, 7F, 9V, 14, 18C, 19F and 23 F. The four meningococcal vaccine results are from the only infant trial in this data base and are a single determination of each of the A, C, W173 and Y specificities. Polio values are ranges for neutralizing activity for Polio 1, 2 and 3, respectively, from left to right. References to the individual trials are contained in supplementary file Database S1.