Table 1. Spearman rank correlation between geometric mean antibody responses and fold range of antibody responses in vaccine trials in infants.
Vaccine | Immunogen | No. of trials | Spearman rank correlation |
Pneumonococcal | 1 | 13 | −0.02 |
3 | 13 | −0.35 | |
4 | 23 | 0.10 | |
5 | 13 | 0.08 | |
14 | 23 | −0.42* | |
18C | 23 | −0.30 | |
19F | 23 | 0.20 | |
23F | 23 | 0.04 | |
6B | 23 | 0.21 | |
7F | 13 | 0.24 | |
9V | 23 | −0.37* | |
HiB | PRP | 28 | −0.37 |
Diphtheria | DT | 30 | −0.11 |
Pertussis | FHA | 13 | −0.19 |
Pertactin | 12 | −0.62* | |
PT | 22 | −0.45* | |
Hepatitis B | HbS | 13 | −0.44* |
Tetanus | TT | 20 | −0.04 |
P 0.017 to 0.045