Figure 2. System A and System N transporters are upregulated in undercut cortex.

Digoxigenin labeled probes for mRNAs of the system A transporters SNAT1 (A) and SNAT2 (B) were used to assess expression of the transporter genes by in situ hybridization. Examination of cortex adjacent to the undercut lesion (right panels) demonstrates an increased signal in deep cortical layers (black arrows top panel, white arrows bottom panel) when compared to the contralateral control cortex (left panels) for both transporter mRNAs. The scale bars indicate 500μm for the low power images and 100μm for high power images.