Cortisol (μg/dL) |
19.6 ± 6.6 |
5.7 ± 4.5 |
Aldosterone (ng/dL) |
7.8 ± 5.5 |
6.4 ± 5.5 |
11-deoxycortisol (ng/dL) |
579.5 ± 264.8 |
177.2 ± 127.0 |
DHEA (μg/dL) |
358.4 ± 260.8 |
43.4 ± 69.5 |
17-hydroxyprogesterone (ng/dL) |
119.8 ± 157.6 |
88.4 ± 124.5 |
Androstenedione (ng/mL) |
0.4 ± 0.3 |
0.1 ± 0.2 |
DHEA-S (μg/dL) |
17.0 ± 22.6 |
7.7 ± 12.1 |
|
30 minute Delta** (mean ± SE)
|
30 minute Delta** (mean ± SE)
|
Cortisol (μg/dL) |
15.1 ± 4.9 |
4.2 ± 3.8 |
Aldosterone (ng/dL) |
7.3 ± 5.7 |
5.8 ± 5.9 |
11-deoxycortisol (ng/dL) |
492.5 ± 245.7 |
143.6 ± 107.6 |
DHEA (μg/dL) |
287.7 ± 226.7 |
10.0 ± 57.1 |
|
60 minute Delta*** (mean ± SE)
|
60 minute Delta*** (mean ± SE)
|
Cortisol (μg/dL) |
19.6 ± 6.6 |
5.6 ± 4.9 |
Aldosterone (ng/dL) |
4.8 ± 4.5 |
4.9 ± 5.8 |
11-deoxycortisol (ng/dL) |
591.5 ± 268.4 |
164.0 ± 131.3 |
DHEA (μg/dL) |
344.6 ± 262.6 |
21.2 ± 103.7 |
3b Distribution of Steroid Peaks following ACTH injection in normal subjects |
STEROID |
Peak at 30 minutes (%) |
Peak at 60 minutes (%) |
Cortisol |
2 |
98 |
Aldosterone |
73 |
27 |
11-deoxycortisol |
15 |
85 |
DHEA |
28 |
72 |
17-hydroxyprogesterone |
36 |
64 |
Androstenedione |
36 |
64 |
DHEA-S |
23 |
77 |
3c Correlation between peak cortisol values and peak values of other steroids |
STEROID |
Correlation coefficient using all subjects |
Correlation coefficient for subjects excluding secondary AI |
Aldosterone |
0.19 |
0.37 |
11-deoxycortisol |
0.67 |
0.59 |
DHEA |
0.48 |
0.38 |
17-hydroxyprogesterone |
0.26 |
0.25 |
Androstenedione |
0.41 |
0.37 |
DHEA-S |
0.33 |
0.18 |