Table 4c.
Number with primary AI | Number with secondary AI | Total | Sensitivity % | Specificity % | PPV % | NPV % | |
---|---|---|---|---|---|---|---|
Cortisol (μg/dL) | |||||||
<5 | 6 | 3 | 9 | 86 | 75 | 67 | 75 |
≥5 | 1 | 9 | 10 | ||||
Total | 7 | 12 | 19 | ||||
Aldosterone (ng/dL) | |||||||
<6 | 7 | 2 | 9 | 100 | 83 | 78 | 100 |
≥6 | 0 | 10 | 10 | ||||
Total | 7 | 12 | 19 | ||||
11-deoxycortisol (ng/dL) | |||||||
<400 | 7 | 9 | 16 | 100 | 25 | 44 | 100 |
≥400 | 0 | 3 | 3 | ||||
Total | 7 | 12 | 19 | ||||
DHEA (ng/dL) | |||||||
<300 | 7 | 11 | 18 | 100 | 8 | 39 | 100 |
≥300 | 0 | 1 | 1 | ||||
Total | 7 | 12 | 19 | ||||
Three-steroid profile (aldosterone < 6 ng/dL, 11-deoxycortisol < 400 ng/dL, DHEA < 300 ng/dL) | |||||||
Yes | 7 | 2 | 9 | 100 | 83 | 78 | 100 |
No | 0 | 10 | 10 | ||||
Total | 7 | 12 | 19 | ||||
Four-steroid profile (cortisol < 5 μg/dL, aldosterone < 6 ng/dL, 11-deoxycortisol < 400 ng/dL, DHEA < 300 ng/dL) | |||||||
Yes | 6 | 1 | 7 | 86 | 92 | 86 | 92 |
No | 1 | 11 | 12 | ||||
Total | 7 | 12 | 19 |
PPV = positive predictive value; NPV = negative predictive value