Table 4c.

Predictive value of selected peak cut-offs for discriminating primary from secondary AI

	Number with primary AI	Number with secondary AI	Total	Sensitivity %	Specificity %	PPV %	NPV %
Cortisol (μg/dL)
<5	6	3	9	86	75	67	75
≥5	1	9	10
Total	7	12	19
Aldosterone (ng/dL)
<6	7	2	9	100	83	78	100
≥6	0	10	10
Total	7	12	19
11-deoxycortisol (ng/dL)
<400	7	9	16	100	25	44	100
≥400	0	3	3
Total	7	12	19
DHEA (ng/dL)
<300	7	11	18	100	8	39	100
≥300	0	1	1
Total	7	12	19
Three-steroid profile (aldosterone < 6 ng/dL, 11-deoxycortisol < 400 ng/dL, DHEA < 300 ng/dL)
Yes	7	2	9	100	83	78	100
No	0	10	10
Total	7	12	19
Four-steroid profile (cortisol < 5 μg/dL, aldosterone < 6 ng/dL, 11-deoxycortisol < 400 ng/dL, DHEA < 300 ng/dL)
Yes	6	1	7	86	92	86	92
No	1	11	12
Total	7	12	19

PPV = positive predictive value; NPV = negative predictive value