Table 4d.
Number with secondary AI | Number with normal status | Total | Sensitivity % | Specificity % | PPV % | NPV % | |
---|---|---|---|---|---|---|---|
Cortisol (μg/dL) used as definition of AI | |||||||
<20 | 12 | 0 | 12 | 100 | 100 | 100 | 100 |
≥20 | 0 | 61 | 61 | ||||
Total | 12 | 61 | 73 | ||||
Aldosterone (ng/dL) | |||||||
<6 | 2 | 10 | 12 | 17 | 84 | 17 | 84 |
≥6 | 10 | 51 | 61 | ||||
Total | 12 | 61 | 73 | ||||
11-deoxycortisol (ng/dL) | |||||||
<400 | 9 | 8 | 17 | 75 | 87 | 53 | 95 |
≥400 | 3 | 53 | 56 | ||||
Total | 12 | 61 | 73 | ||||
DHEA (ng/dL) | |||||||
<300 | 11 | 20 | 31 | 92 | 67 | 35 | 98 |
≥300 | 1 | 41 | 42 | ||||
Total | 12 | 61 | 73 | ||||
Three-steroid profile (aldosterone ≥ 6 ng/dL, 11-deoxycortisol < 400 ng/dL, DHEA < 300 ng/dL) | |||||||
Yes | 7 | 1 | 8 | 58 | 98 | 88 | 92 |
No | 5 | 60 | 65 | ||||
Total | 12 | 61 | 73 | ||||
Two-steroid profile (11-deoxycortisol < 400 ng/dL, DHEA < 300 ng/dL) | |||||||
Yes | 8 | 1 | 9 | 67 | 98 | 89 | 94 |
No | 4 | 60 | 64 | ||||
Total | 12 | 61 | 73 |
PPV = positive predictive value; NPV = negative predictive value