Table 1. Analgesic parameters.

Onset and recovery times from sensory block are compared among various groups. Data were derived from the sensory block measurement in rat sciatic nerve (mean ± SEM) as shown in Fig. 5A, 6A, and 7A. Epinephrine was diluted to 1:100,000 (or 10 μg/ml). One-way analysis of variance (ANOVA) was used to test for overall mean differences in onset to full sensory block and complete recovery from sensory block values in 2% lidocaine, 0.375 mM BLA, 0.375 mM BLA+2% lidocaine, and 0.375 mM BLA+epinephrine groups. Given a significant F test (P < 0.05), pairwise post-hoc Bonferroni tests were performed for multiple pairwise comparisons.

Group	N	Onset to full sensory block (in minutes)	Recovery from sensory block (in minutes)
2% lidocaine	6	3.33 ± 0.21	66.67 ± 9.19
0.375mM BLA	6	41.67 ± 1.67 **	230.00 ± 6.32 **
0.375mM BLA+2% lidocaine	6	3.50 ± 0.22	330.00 ± 10.95 **,‡‡
0.375mM BLA+epinephrine	6	35.83 ± 4.90 **	440.00 ± 12.65 **,‡‡

^**P < 0.001, compared with the 2% lidocaine group.

^‡‡P < 0.001, compared with the 0.375 mM BLA group. The GEE statistic analyses likewise agreed with these conclusions.