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. Author manuscript; available in PMC: 2008 Jun 1.
Published in final edited form as: Neurobiol Dis. 2007 Mar 24;26(3):688–695. doi: 10.1016/j.nbd.2007.03.006

Figure 5.

Figure 5

Ad-GFAP-HO-1 protects wild-type astrocytes from hemin. Phase-contrast photomicrographs of astrocyte cultures, 24 hours after: A) medium exchange only; B) treatment with 10 μM hemin; the culture monolayer is no longer confluent, and most remaining astrocytes have developed a granular appearance with pyknotic nuclei; C) treatment with 10 μM hemin after 24 hour incubation with 100 MOI Ad-Null; D) treatment with 10 μM hemin after 24 hour incubation with 100 MOI Ad-GFAP-HO-1; culture monolayer remains intact. Scale bar = 50 μm.