Table 6.
Thermodynamic degree of coupling (q) and optimal efficiency (ηopt) of the oxidative phosphorylation in liver isolated mitochondria from pair-fed (PF), control (CON) and dexamethasone (DEX)-treated rats. (Values expressed as mean ± standard deviation for eight rats per group)
Respiratory substrates | Parameters | DEX-treated | PF | CON | ANOVA |
---|---|---|---|---|---|
Glutamate | q | 0.903 ± 0.044 | 0.896 ± 0.040 | 0.942 ± 0.013 | NS |
ηopt | 0.413 ± 0.092 | 0.396 ± 0.080 | 0.500 ± 0.039 | NS | |
Succinate | q | 0.896 ± 0.019‡** | 0.923 ± 0.022 | 0.922 ± 0.011 | P < 0.05 |
ηopt | 0.387 ± 0.038‡** | 0.451 ± 0.052 | 0.439 ± 0.028 | P < 0.05 | |
Ascorbate/TMPD | q | 0.656 ± 0.028†* | 0.708 ± 0.024 | 0.706 ± 0.028 | P < 0.005 |
ηopt | 0.140 ± 0.016†* | 0.173 ± 0.016 | 0.173 ± 0.018 | P < 0.005 |
P < 0.05 vs. PF;
P < 0.05 vs. CON;
P < 0.01 vs. PF;
P < 0.01 vs. CON.
NS: not significant.
For details of procedures see materials and methods section.