Table 3 Comparison between patients with catastrophic antiphospholipid syndrome related and those not related to pregnancy or puerperium.
| Catastrophic APS related to pregnancy and puerperium n = 15 (%) | Catastrophic APS not related to pregnancy or puerperium n = 240 (%) | p Value | |
|---|---|---|---|
| Feature | |||
| Catastrophic APS as a first manifestation | 3 (20) | 114 (47) | 0.05 |
| Previous APS features | 10 (67) | 127 (53) | NS |
| Previous abortions | 9 (60) | 41 (17) | <0.001 |
| DVT | 3 (20) | 76 (32) | NS |
| Peripheral arterial thrombosis | 0 (0) | 27 (11) | NS |
| Cardiac involvement | 3 (20) | 128 (33) | 0.02 |
| Valvular disease | 1 (7) | 49 (20) | NS |
| Pulmonary involvement | 11 (73) | 159 (66) | NS |
| ARDS | 5 (33) | 60 (25) | NS |
| Renal involvement | 10 (67) | 175 (73) | NS |
| Cerebral involvement | 9 (60) | 151 (63) | NS |
| Cutaneous involvement | 5 (33) | 124 (52) | NS |
| Livedo reticularis | 2 (13) | 66 (27) | 0.025 |
| Death | 7 (47) | 111 (46) | NS |
ARDS, acute respiratory distress syndrome; DVT, deep venous thrombosis; NS, not significant.