Table 2 Absence of rheumatoid arthritis linkage to the IRF5rs2004640‐T allele using the transmission disequilibrium test.

Sample	Transmitted	Untransmitted	T (%)	p Value*
Global set (n = 95)	43	45	49	0.76
RF+ (n = 76)	32	33	49	0.90
AID+ (n = 31)	14	16	47	0.71
PTPN22‐1858T+ (n = 32)	12	19	39	0.21

AID, autoimmune disease; RF, rheumatoid factor.

AID+, subgroup of families with at least one member (up to the second‐degree relatives) with an AID; n, number of genotyped trio in each sample; PTPN22‐1858T+, subgroup of families with index RA case carrying the PTPN22‐1858T allele in the genotype; RF+, subgroup of families with index rheumatoid arthritis (RA) case positive for RF; T, percentage of transmission of the rs2004640‐T allele from heterozygotic parents to RA cases, compared with Mendel's expectation of 50%.

*Using the χ² test with 1 degree of freedom.