Table 2 Ex vivo interleukin 1β and interleukin 1 receptor antagonist production*.

Cytokine	Patients with RA (n = 76)	Controls (n = 63)	p Value
IL1β	1536 (606–2854) †	2773 (1487–4901)	<0.001
IL1Ra	29 010 (20 459–41 195)	18 234 (14 387–22 293)	<0.001

IL1β, interleukin 1 beta; IL1Ra, interleukin 1 receptor antagonist; RA, rheumatoid arthritis.

Of patients with recent‐onset RA and healthy controls, on stimulation with lipopolysaccharide; pg/ml; median (interquartile range).

†n = 75 patients.