Table 1 The relation between intra‐articular 90Y distribution and the clinical effect of RSO, radiological class and leakage (n = 78 knees)*.
| Mainly diffuse distribution n = 42 | Mainly focal distribution n = 36 | p | |
|---|---|---|---|
| Composite change index (CCI, 0–12) | |||
| CCI, classified | n (%) | n (%) | 0.6 |
| 0–4 | 19 (45) | 12 (33) | |
| 4–8 | 15 (36) | 16 (45) | |
| 8–12 | 8 (19) | 8 (22) | |
| Median (95% LCL‐ 95% UCL) | 5 (3–7) | 7 (4–8) | 0.5 |
| Responders (CCI ⩾6), n (%) | 17 (40) | 20 (56) | 0.3 |
| Radiological class | n (%) | n (%) | 0.2 |
| I | 14 (35) | 7 (20) | |
| II | 25 (63) | 28 (80) | |
| Leakage (% of given dose)† | |||
| to the liver | |||
| Number of assessments | 18 | 15 | |
| mean (SD) | 0.2 (0.4) | 0.9 (0.8) | 0.0004 |
| leakage to liver, classified: | n | n | 0.004 |
| 0 | 15 | 3 | |
| 0–1 | 2 | 7 | |
| 1–2 | 1 | 4 | |
| 2–3 | 0 | 1 | |
| to the spleen | |||
| number of assessments | 5 | 13 | |
| mean (SD) | 0.6 (0.4) | 1.6 (1.3) | 0.09 |
| leakage to spleen, classified: | n | n | 0.2 |
| 0 | 0 | 1 | |
| 0–1 | 5 | 5 | |
| 1–2 | 0 | 4 | |
| 2–3 | 0 | 2 | |
| 3–4 | 0 | 0 | |
| 4–5 | 0 | 1 |
*78 knees: rheumatoid arthritis 22, undifferentiated arthritis 33, psoriatic arthritis 17, osteoarthritis 1, pigmented villonodular synovitis 1, synovial chondromatosis 1, ankylosing spondylitis 1, undifferentiated seronegative spondyloarthropathy 1, calcium pyrophosphate arthropathy 1.
†Counts, expressed as percentage of total counts corresponding with the whole injected dose.