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. 2007 Mar 12;91(8):1000–1004. doi: 10.1136/bjo.2006.108019

Table 2 Main anatomical site of abnormality, and underlying aetiology in 1935 severely visually impaired and blind children, by gender and age.

Boys Girls 0–5 years 6–10 years 11–15 years Total
n (%) n (%) n (%) n (%) n (%) n (%)
Anatomical Whole globe 155 (12.7) 98 (13.7) 48 (16.2) 85 (13.9) 120 (11.7) 253 (13.1)
p<0.001* Cornea 301 (24.7) 213 (29.8) 39 (13.1) 140 (22.9) 335 (32.6) 514 (26.6)
p<0.001† Lens 451 (37.0) 178 (24.9) 129 (43.4) 230 (37.6) 270 (26.3) 629 (32.5)
Uvea 21 (1.7) 17 (2.4) 1 (0.3) 10 (1.6) 27 (2.6) 38 (2.0)
Retina 148 (12.1) 97 (13.6) 36 (12.1) 71 (11.6) 138 (13.4) 245 (12.7)
Optic nerve 88 (7.2) 66 (9.2) 21 (7.1) 45 (7.4) 88 (8.6) 154 (8.0)
Glaucoma 47 (3.9) 36 (5.0) 19 (6.4) 26 (4.3) 38 (3.7) 83 (4.3)
Other‡ 9 (0.7) 10 (1.4) 4 (1.35) 4 (0.7) 11 (1.1) 19 (1.0)
Aetiology Hereditary 176 (14.4) 115 (16.1) 55 (18.5) 98 (16.0) 138 (13.4) 291 (15.0)
p = 0.06 Childhood factor 353 (28.9) 240 (33.6) 35 (11.8) 163 (26.7) 395 (38.5) 593 (30.7)
p<0.001† Other§ 10 (0.8) 7 (1.0) 2 (0.7) 4 (0.7) 11 (1.1) 17 (0.9)
Unknown 681 (55.8) 353 (49.4) 205 (69.0) 346 (56.6) 483 (47.0) 1034 (53.4)
Type of Preventable 315 (25.8) 222 (31.1) 34 (11.5) 146 (23.9) 357 (34.8) 537 (27.8)
blindness Treatable 549 (45.0) 252 (35.2) 157 (52.9) 272 (44.5) 372 (36.2) 801 (41.4)
p<0.001* Unavoidable 356 (29.2) 241 (33.7) 106 (35.7) 193 (31.6) 298 (29.0) 597 (30.8)
p<0.001† Total 1220 (100) 715 (100) 297 (100) 611 (100) 1027 (100) 1935 (100)

2, showing significant differences between genders in anatomical site and type of blindness.

†χ2, showing significant differences between age groups in anatomical site, aetiology and type of blindness.

‡Includes children that had either no anatomical abnormality (n = 14) or no anterior segment abnormality, but the posterior segment was not examined (n = 5) because the child was too young and/or uncooperative and/or had multiple disabilities.

§Perinatal, intrauterine.