Table 1 Number of rectally hypersensitive IBS patients reporting the most commonly reported adverse events following treatment with pregabalin and placebo control.
| Pregabalin (n = 14) | Placebo (n = 12) | |
|---|---|---|
| Body as a whole | 1 | 9 |
| Accidental injury | 0 | 1 |
| Asthenia | 1 | 0 |
| Headache | 0 | 8 |
| Infection | 0 | 2 |
| Malaise | 1 | 0 |
| Pelvic pain | 0 | 1 |
| Digestive | 4 | 5 |
| Abdominal pain | 0 | 3 |
| Anorexia | 0 | 1 |
| Constipation | 3 | 2 |
| Flatulence | 0 | 2 |
| Nausea | 1 | 1 |
| Vomiting | 1 | 0 |
| Nervous system | 12 | 4 |
| Amnesia | 1 | 0 |
| Confusion | 1 | 0 |
| Dizziness | 10 | 1 |
| Euphoria | 1 | 0 |
| In‐coordination | 3 | 0 |
| Insomnia | 0 | 1 |
| Somnolence | 5 | 2 |
| Speech disorder | 1 | 0 |
| Thinking difficulty | 2 | 0 |
| Respiratory | 1 | 1 |
| Cough increase | 1 | 0 |
| Pharyngitis | 1 | 0 |
| Sinusitis | 0 | 1 |
| Skin and appendages | 0 | 1 |
| Sweating | 0 | 1 |
| Special senses | 3 | 1 |
| Amblyopia | 2 | 1 |
| Eye haemorrhage | 1 | 0 |
| Urogenital | 0 | 1 |
| Polyuria | 0 | 1 |