Figure 6 IL31 mRNA expression is not increased in murine models of Th1 mediated intestinal inflammation. (A) IL31 expression was similar in ileal and colonic epithelial cells of TNFΔARE mice (n = 9) compared to C57BL/6 wild type mice (n = 9). Ileal mRNA expression in wild type mice was arbitrarily set to 1.0 and all other expression levels were calculated proportionally as fold increase. Data are presented as mean (SEM). (B) OSMR mRNA expression was not significantly different in TNFΔARE mice compared to wild type mice (p = 0.26). (C) TNF‐α mRNA expression was significantly higher in TNFΔARE mice compared to wild type mice (p<0.01). (D) IL31, IL31Rα, and OSMR mRNA expression were not significantly increased in C57BL/6 mice infected with murine cytomegalovirus (n = 10) compared to uninfected C57BL/6 mice (n = 4).