Figure 5 Panc02 cells can be recognised and killed by antigen‐specific cytotoxic T lymphocytes in a major histocompatibility complex class I‐restricted manner. Panc02 cells were loaded with SIINFEKL or irrelevant TRP2 peptide and co‐cultured with splenocytes derived either from wild‐type C57BL/6 mice or from transgenic OT‐1 mice in a ⁵¹Cr‐release assay at effector:target ratios from 3.125:1 to 100:1. EL4 cells loaded with SIINFEKL or irrelevant TRP2 peptide and co‐cultured with splenocytes from transgenic OT‐1 mice served as positive controls in the ⁵¹Cr‐release assay.