Figure 7 Synergistic effect of dendritic cell (DC)‐based vaccination and gemcitabine is preserved after 50% dose reduction of chemotherapy. Female 6‐ to 10‐week old C57BL/6 mice were challenged subcutaneously with 0.5×10⁶ Panc02 cells. Fourteen days after tumour inoculation, mice were either left untreated (n = 7), vaccinated with Panc02‐pulsed DCs at weekly intervals (n = 7) or treated with intraperitoneal gemcitabine (Gem 50 mg/kg body weight) twice weekly (n = 6). Mice treated with the combination of DC vaccine and chemotherapy received either 50 mg/kg body weight (n = 6) or 25 mg/kg body weight of gemcitabine (n = 8). Survival rates in the different treatment groups are depicted as Kaplan–Meier graphs.